PRINCIPLE – COVID-19 research trial

Castle Partnership is supporting vital COVID-19 research. As part of this, we are helping to carry out a UK Government priority research study called PRINCIPLE. The PRINCIPLE trial aims to find medicines that can help people with COVID-19 symptoms get better quickly and stop them needing to go to hospital. The trial is recruiting participants through GP practices across the UK.

If you have symptoms of COVID-19, and are aged 65 or over or are aged 50-64 and have an existing health condition including:

  • weakened immune system due to a serious illness or medication (e.g. chemotherapy);
  • heart disease;
  • high blood pressure;
  • asthma;
  • lung disease;
  • Diabetes – not treated with insulin;
  • liver disease;
  • stroke or neurological problem.

you may be eligible to join this important study.

Visit for more information including how to take part in this vital research trial.